Enhanced Susceptibility of Ogg1 Mutant Mice to Multiorgan Carcinogenesis

The role of deficiency of oxoguanine glycosylase 1 (Ogg1) Mmh homolog, a repair enzyme of the 8-hydroxy-2’-deoxyguanosine (8-OHdG) residue in DNA, was investigated using the multiorgan carcinogenesis bioassay in mice. A total of 80 male and female six-week-old mice of C57BL/6J background carrying a...

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Detalles Bibliográficos
Autores principales: Kakehashi, Anna, Ishii, Naomi, Okuno, Takahiro, Fujioka, Masaki, Gi, Min, Wanibuchi, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578188/
https://www.ncbi.nlm.nih.gov/pubmed/28820464
http://dx.doi.org/10.3390/ijms18081801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578188/
https://www.ncbi.nlm.nih.gov/pubmed/28820464
http://dx.doi.org/10.3390/ijms18081801

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