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Junk food diet-induced obesity increases D2 receptor autoinhibition in the ventral tegmental area and reduces ethanol drinking

Similar to drugs of abuse, the hedonic value of food is mediated, at least in part, by the mesostriatal dopamine (DA) system. Prolonged intake of either high calorie diets or drugs of abuse both lead to a blunting of the DA system. Most studies have focused on DAergic alterations in the striatum, bu...

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Detalles Bibliográficos
Autores principales: Cook, Jason B., Hendrickson, Linzy M., Garwood, Grant M., Toungate, Kelsey M., Nania, Christina V., Morikawa, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578487/
https://www.ncbi.nlm.nih.gov/pubmed/28859110
http://dx.doi.org/10.1371/journal.pone.0183685

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