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Local inner ear application of dexamethasone in cochlear implant models is safe for auditory neurons and increases the neuroprotective effect of chronic electrical stimulation

Dexamethasone (DEX) can reduce fibrous tissue growth as well as loss of residual hearing which may occur after cochlear implantation. Little is known about the effect of local inner ear DEX treatment on the spiral ganglion neurons (SGN), which are the target of the electrical stimulation with a coch...

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Detalles Bibliográficos
Autores principales: Scheper, Verena, Hessler, Roland, Hütten, Mareike, Wilk, Maciej, Jolly, Claude, Lenarz, Thomas, Paasche, Gerrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578571/
https://www.ncbi.nlm.nih.gov/pubmed/28859106
http://dx.doi.org/10.1371/journal.pone.0183820