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Directed evolution provides insight into conformational substrate sampling by SrtA
The Sortase family of transpeptidases are found in numerous gram-positive bacteria and involved in divergent physiological processes including anchoring of surface proteins to the cell wall as well as pili assembly. As essential proteins, sortase enzymes have been the focus of considerable interest...
Autores principales: | Suliman, Muna, Santosh, Vishaka, Seegar, Tom C. M., Dalton, Annamarie C., Schultz, Kathryn M., Klug, Candice S., Barton, William A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578623/ https://www.ncbi.nlm.nih.gov/pubmed/28859178 http://dx.doi.org/10.1371/journal.pone.0184271 |
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