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TSS-Seq analysis of low pH-induced gene expression in intercalated cells in the renal collecting duct

Metabolic acidosis often results from chronic kidney disease; in turn, metabolic acidosis accelerates the progression of kidney injury. The mechanisms for how acidosis facilitates kidney injury are not fully understood. To investigate whether low pH directly affects the expression of genes controlli...

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Detalles Bibliográficos
Autores principales: Izumi, Yuichiro, Inoue, Hideki, Nakayama, Yushi, Eguchi, Koji, Yasuoka, Yukiko, Matsuo, Naomi, Nonoguchi, Hiroshi, Kakizoe, Yutaka, Kuwabara, Takashige, Mukoyama, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578634/
https://www.ncbi.nlm.nih.gov/pubmed/28859164
http://dx.doi.org/10.1371/journal.pone.0184185