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Asporin-deficient mice have tougher skin and altered skin glycosaminoglycan content and structure

The main structural component of connective tissues is fibrillar, cross-linked collagen whose fibrillogenesis can be modulated by Small Leucine-Rich Proteins/Proteoglycans (SLRPs). Not all SLRPs’ effects on collagen and extracellular matrix in vivo have been elucidated; one of the less investigated...

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Detalles Bibliográficos
Autores principales: Maccarana, Marco, Svensson, René B., Knutsson, Anki, Giannopoulos, Antonis, Pelkonen, Mea, Weis, MaryAnn, Eyre, David, Warman, Matthew, Kalamajski, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578652/
https://www.ncbi.nlm.nih.gov/pubmed/28859141
http://dx.doi.org/10.1371/journal.pone.0184028