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Crosstalk between the tricarboxylic acid cycle and peptidoglycan synthesis in Caulobacter crescentus through the homeostatic control of α-ketoglutarate
To achieve robust replication, bacteria must integrate cellular metabolism and cell wall growth. While these two processes have been well characterized, the nature and extent of cross-regulation between them is not well understood. Here, using classical genetics, CRISPRi, metabolomics, transcriptomi...
Autores principales: | Irnov, Irnov, Wang, Zhe, Jannetty, Nicholas D., Bustamante, Julian A., Rhee, Kyu Y., Jacobs-Wagner, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578688/ https://www.ncbi.nlm.nih.gov/pubmed/28827812 http://dx.doi.org/10.1371/journal.pgen.1006978 |
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