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The role of the C-terminal D0 domain of flagellin in activation of Toll like receptor 5

Flagellin is a wide-spread bacterial virulence factor sensed by the membrane-bound Toll-like receptor 5 (TLR5) and by the intracellular NAIP5/NLRC4 inflammasome receptor. TLR5 recognizes a conserved region within the D1 domain of flagellin, crucial for the interaction between subunits in the flagell...

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Detalles Bibliográficos
Autores principales:	Forstnerič, Vida, Ivičak-Kocjan, Karolina, Plaper, Tjaša, Jerala, Roman, Benčina, Mojca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578693/ https://www.ncbi.nlm.nih.gov/pubmed/28827825 http://dx.doi.org/10.1371/journal.ppat.1006574

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