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Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma
Transport of solutes through brain involves diffusion and convection. The importance of convective flow in the subarachnoid and paravascular spaces has long been recognized; a recently proposed ‘glymphatic’ clearance mechanism additionally suggests that aquaporin-4 (AQP4) water channels facilitate c...
Autores principales: | Smith, Alex J, Yao, Xiaoming, Dix, James A, Jin, Byung-Ju, Verkman, Alan S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578736/ https://www.ncbi.nlm.nih.gov/pubmed/28826498 http://dx.doi.org/10.7554/eLife.27679 |
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