Cargando…
Insulin Resistance in Vascular Endothelial Cells Promotes Intestinal Tumor Formation
The risk of several cancers, including colorectal cancer, is increased in patients with obesity and type 2 diabetes, conditions characterized by hyperinsulinemia and insulin resistance. Because hyperinsulinemia itself is an independent risk factor for cancer development, we examined tissue-specific...
Autores principales: | Wang, Xuanchun, Häring, Max-Felix, Rathjen, Thomas, Lockhart, Samuel M., Sørensen, Ditte, Ussar, Siegfried, Rasmussen, Lars Melholt, Bertagnolli, Monica M., Kahn, C. Ronald, Rask-Madsen, Christian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578899/ https://www.ncbi.nlm.nih.gov/pubmed/28459466 http://dx.doi.org/10.1038/onc.2017.107 |
Ejemplares similares
-
Insulin Downregulates the Transcriptional Coregulator CITED2, an Inhibitor of Proangiogenic Function in Endothelial Cells
por: Wang, Xuanchun, et al.
Publicado: (2016) -
SHP-1 activation inhibits vascular smooth muscle cell proliferation and intimal hyperplasia in a rodent model of insulin resistance and diabetes
por: Qi, Weier, et al.
Publicado: (2016) -
Response to Comment on Ussar et al. Regulation of Glucose Uptake and Enteroendocrine Function by the Intestinal Epithelial Insulin Receptor. Diabetes 2017;66:886–896
por: Kahn, C. Ronald, et al.
Publicado: (2017) -
Glypican-4 Enhances Insulin Signaling via Interaction With the Insulin Receptor and Serves as a Novel Adipokine
por: Ussar, Siegfried, et al.
Publicado: (2012) -
Insulin receptor trafficking steers insulin action
por: Hausmann, Simone, et al.
Publicado: (2016)