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Age Related Differences in Responsiveness to Sildenafil and Tamsulosin are due to Myogenic Smooth Muscle Tone in the Human Prostate

Lower urinary tract symptoms (LUTS) due to Benign Prostatic Hyperplasia (BPH) are highly prevalent in older men, having a profound impact on patient quality of life. Current therapeutics for BPH/LUTS target neurogenic smooth muscle tone, but response is unpredictable and many patients fail to respon...

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Detalles Bibliográficos
Autores principales:	Lee, Sophie N., Chakrabarty, Basu, Wittmer, Brad, Papargiris, Melissa, Ryan, Andrew, Frydenberg, Mark, Lawrentschuk, Nathan, Middendorff, Ralf, Risbridger, Gail P., Ellem, Stuart J., Exintaris, Betty
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578961/ https://www.ncbi.nlm.nih.gov/pubmed/28860509 http://dx.doi.org/10.1038/s41598-017-07861-x

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