Quantifying perinatal transmission of Hepatitis B viral quasispecies by tag linkage deep sequencing

Despite full immunoprophylaxis, mother-to-child transmission (MTCT) of Hepatitis B Virus still occurs in approximately 2–5% of HBsAg positive mothers. Little is known about the bottleneck of HBV transmission and the evolution of viral quasispecies in the context of MTCT. Here we adopted a newly deve...

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Detalles Bibliográficos
Autores principales: Du, Yushen, Chi, Xiumei, Wang, Chong, Jiang, Jing, Kong, Fei, Yan, Hongqing, Wang, Xiaomei, Li, Jie, Wu, Nicholas C., Dai, Lei, Zhang, Tian-Hao, Shu, Sara, Zhou, Jian, Yoshizawa, Janice M., Li, Xinmin, Bhattacharya, Debika, Wu, Ting-ting, Niu, Junqi, Sun, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578979/
https://www.ncbi.nlm.nih.gov/pubmed/28860476
http://dx.doi.org/10.1038/s41598-017-10591-9

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