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Involvement of mTOR-autophagy in the selection of primitive mesenchymal stem cells in chitosan film 3-dimensional culture

Mesenchymal stem cells (MSCs) in conventional monolayer culture are heterogeneous and contain a significant portion of senescent cells. MSCs cultured on chitosan film form 3-dimenional spheres, increase in stemness and differentiation capability; however, the underlying mechanisms remain elusive. We...

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Detalles Bibliográficos
Autores principales:	Chiu, Hsiao-Ying, Tsay, Yeou-Guang, Hung, Shih-Chieh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578982/ https://www.ncbi.nlm.nih.gov/pubmed/28860574 http://dx.doi.org/10.1038/s41598-017-10708-0

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