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Delay discounting is associated with the fractional amplitude of low-frequency fluctuations and resting-state functional connectivity in late adolescence
As a component of self-regulation, delay discounting (DD) refers to an individual’s tendency to prefer smaller-but-sooner rewards over larger-but-later rewards and plays an essential role in many aspects of human behavior. Although numerous studies have examined the neural underpinnings of DD in adu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579001/ https://www.ncbi.nlm.nih.gov/pubmed/28860514 http://dx.doi.org/10.1038/s41598-017-11109-z |
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author | Wang, Song Zhou, Ming Chen, Taolin Yang, Xun Chen, Guangxiang Gong, Qiyong |
author_facet | Wang, Song Zhou, Ming Chen, Taolin Yang, Xun Chen, Guangxiang Gong, Qiyong |
author_sort | Wang, Song |
collection | PubMed |
description | As a component of self-regulation, delay discounting (DD) refers to an individual’s tendency to prefer smaller-but-sooner rewards over larger-but-later rewards and plays an essential role in many aspects of human behavior. Although numerous studies have examined the neural underpinnings of DD in adults, there are far fewer studies focusing on the neurobiological correlates underlying DD in adolescents. Here, we investigated the associations between individual differences in DD and the fractional amplitude of low-frequency fluctuations (fALFF) and resting-state functional connectivity (RSFC) in 228 high school students using resting-state functional magnetic resonance imaging (RS-fMRI). At the regional level, we found an association between higher DD and greater fALFF in the dorsal anterior cingulate cortex (dACC), which is involved in conflict monitoring and strategy adaptation. At the connectivity level, DD was positively correlated with the RSFC between the dACC and the left dorsolateral prefrontal cortex (DLPFC), a critical functional circuit in the cognitive control network. Furthermore, these effects persisted even after adjusting for the influences of general intelligence and trait impulsivity. Overall, this study reveals the fALFF and RSFC as the functional brain basis of DD in late adolescents, aiding to strengthen and corroborate our understanding of the neural underpinnings of DD. |
format | Online Article Text |
id | pubmed-5579001 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-55790012017-09-06 Delay discounting is associated with the fractional amplitude of low-frequency fluctuations and resting-state functional connectivity in late adolescence Wang, Song Zhou, Ming Chen, Taolin Yang, Xun Chen, Guangxiang Gong, Qiyong Sci Rep Article As a component of self-regulation, delay discounting (DD) refers to an individual’s tendency to prefer smaller-but-sooner rewards over larger-but-later rewards and plays an essential role in many aspects of human behavior. Although numerous studies have examined the neural underpinnings of DD in adults, there are far fewer studies focusing on the neurobiological correlates underlying DD in adolescents. Here, we investigated the associations between individual differences in DD and the fractional amplitude of low-frequency fluctuations (fALFF) and resting-state functional connectivity (RSFC) in 228 high school students using resting-state functional magnetic resonance imaging (RS-fMRI). At the regional level, we found an association between higher DD and greater fALFF in the dorsal anterior cingulate cortex (dACC), which is involved in conflict monitoring and strategy adaptation. At the connectivity level, DD was positively correlated with the RSFC between the dACC and the left dorsolateral prefrontal cortex (DLPFC), a critical functional circuit in the cognitive control network. Furthermore, these effects persisted even after adjusting for the influences of general intelligence and trait impulsivity. Overall, this study reveals the fALFF and RSFC as the functional brain basis of DD in late adolescents, aiding to strengthen and corroborate our understanding of the neural underpinnings of DD. Nature Publishing Group UK 2017-08-31 /pmc/articles/PMC5579001/ /pubmed/28860514 http://dx.doi.org/10.1038/s41598-017-11109-z Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Wang, Song Zhou, Ming Chen, Taolin Yang, Xun Chen, Guangxiang Gong, Qiyong Delay discounting is associated with the fractional amplitude of low-frequency fluctuations and resting-state functional connectivity in late adolescence |
title | Delay discounting is associated with the fractional amplitude of low-frequency fluctuations and resting-state functional connectivity in late adolescence |
title_full | Delay discounting is associated with the fractional amplitude of low-frequency fluctuations and resting-state functional connectivity in late adolescence |
title_fullStr | Delay discounting is associated with the fractional amplitude of low-frequency fluctuations and resting-state functional connectivity in late adolescence |
title_full_unstemmed | Delay discounting is associated with the fractional amplitude of low-frequency fluctuations and resting-state functional connectivity in late adolescence |
title_short | Delay discounting is associated with the fractional amplitude of low-frequency fluctuations and resting-state functional connectivity in late adolescence |
title_sort | delay discounting is associated with the fractional amplitude of low-frequency fluctuations and resting-state functional connectivity in late adolescence |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579001/ https://www.ncbi.nlm.nih.gov/pubmed/28860514 http://dx.doi.org/10.1038/s41598-017-11109-z |
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