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A mix-and-click method to measure amyloid-β concentration with sub-micromolar sensitivity

Aggregation of amyloid-β (Aβ) protein plays a central role in Alzheimer's disease. Because protein aggregation is a concentration-dependent process, rigorous investigations require accurate concentration measurements. Owing to the high aggregation propensity of Aβ protein, working solutions of...

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Detalles Bibliográficos
Autores principales: Xue, Christine, Lee, Yoon Kyung, Tran, Joyce, Chang, Dennis, Guo, Zhefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579099/
https://www.ncbi.nlm.nih.gov/pubmed/28878984
http://dx.doi.org/10.1098/rsos.170325