Cargando…

Differential metal-binding properties of dynamic acylhydrazone polymers and their sensing applications

As one of common dynamic covalent bonds, acylhydrazone bond plays an important role in developing intelligent responsive materials. In this report, we present acylhydrazone-based dynamic polymers with multi-stimuli responsiveness, particularly metal recognition behaviours and their modulation. A ser...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Siheng, Li, Lijie, Vohra, Ismail, Zha, Daijun, You, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579109/
https://www.ncbi.nlm.nih.gov/pubmed/28878993
http://dx.doi.org/10.1098/rsos.170466
_version_ 1783260641937588224
author Gao, Siheng
Li, Lijie
Vohra, Ismail
Zha, Daijun
You, Lei
author_facet Gao, Siheng
Li, Lijie
Vohra, Ismail
Zha, Daijun
You, Lei
author_sort Gao, Siheng
collection PubMed
description As one of common dynamic covalent bonds, acylhydrazone bond plays an important role in developing intelligent responsive materials. In this report, we present acylhydrazone-based dynamic polymers with multi-stimuli responsiveness, particularly metal recognition behaviours and their modulation. A series of polyacylhydrazones with different metal-binding sites were designed and prepared in a modular fashion. Titration of these receptors with a diverse set of metal ions, including Cu(2+), Zn(2+) and La(3+), resulted in unique optical changes, and both the sensitivity and selectivity profiles can be regulated. Moreover, the metal-binding feature was facilely modulated by changing the solvent. The addition of weakly basic anions was employed to further fine-tune the responsiveness of the polymers by taking advantage of the cooperative effect with metal coordination. Finally, the sensitive detection of 6-mercaptopurine and pyrophosphate was achieved to demonstrate the application potential of these systems.
format Online
Article
Text
id pubmed-5579109
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher The Royal Society Publishing
record_format MEDLINE/PubMed
spelling pubmed-55791092017-09-06 Differential metal-binding properties of dynamic acylhydrazone polymers and their sensing applications Gao, Siheng Li, Lijie Vohra, Ismail Zha, Daijun You, Lei R Soc Open Sci Chemistry As one of common dynamic covalent bonds, acylhydrazone bond plays an important role in developing intelligent responsive materials. In this report, we present acylhydrazone-based dynamic polymers with multi-stimuli responsiveness, particularly metal recognition behaviours and their modulation. A series of polyacylhydrazones with different metal-binding sites were designed and prepared in a modular fashion. Titration of these receptors with a diverse set of metal ions, including Cu(2+), Zn(2+) and La(3+), resulted in unique optical changes, and both the sensitivity and selectivity profiles can be regulated. Moreover, the metal-binding feature was facilely modulated by changing the solvent. The addition of weakly basic anions was employed to further fine-tune the responsiveness of the polymers by taking advantage of the cooperative effect with metal coordination. Finally, the sensitive detection of 6-mercaptopurine and pyrophosphate was achieved to demonstrate the application potential of these systems. The Royal Society Publishing 2017-08-30 /pmc/articles/PMC5579109/ /pubmed/28878993 http://dx.doi.org/10.1098/rsos.170466 Text en © 2017 The Authors. http://creativecommons.org/licenses/by/4.0/ Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.
spellingShingle Chemistry
Gao, Siheng
Li, Lijie
Vohra, Ismail
Zha, Daijun
You, Lei
Differential metal-binding properties of dynamic acylhydrazone polymers and their sensing applications
title Differential metal-binding properties of dynamic acylhydrazone polymers and their sensing applications
title_full Differential metal-binding properties of dynamic acylhydrazone polymers and their sensing applications
title_fullStr Differential metal-binding properties of dynamic acylhydrazone polymers and their sensing applications
title_full_unstemmed Differential metal-binding properties of dynamic acylhydrazone polymers and their sensing applications
title_short Differential metal-binding properties of dynamic acylhydrazone polymers and their sensing applications
title_sort differential metal-binding properties of dynamic acylhydrazone polymers and their sensing applications
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579109/
https://www.ncbi.nlm.nih.gov/pubmed/28878993
http://dx.doi.org/10.1098/rsos.170466
work_keys_str_mv AT gaosiheng differentialmetalbindingpropertiesofdynamicacylhydrazonepolymersandtheirsensingapplications
AT lilijie differentialmetalbindingpropertiesofdynamicacylhydrazonepolymersandtheirsensingapplications
AT vohraismail differentialmetalbindingpropertiesofdynamicacylhydrazonepolymersandtheirsensingapplications
AT zhadaijun differentialmetalbindingpropertiesofdynamicacylhydrazonepolymersandtheirsensingapplications
AT youlei differentialmetalbindingpropertiesofdynamicacylhydrazonepolymersandtheirsensingapplications