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Detection of dynamic substrate binding using MRI

Magnetic Resonance Imaging (MRI) is rarely used for molecular binding studies and never without synthetic metallic labels. We designed an MRI approach that can specifically detect the binding of natural substrates (i.e. no chemical labels). To accomplish such detection of substrate-target interactio...

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Detalles Bibliográficos
Autores principales: Yadav, Nirbhay N., Yang, Xing, Li, Yuguo, Li, Wenbo, Liu, Guanshu, van Zijl, Peter C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579242/
https://www.ncbi.nlm.nih.gov/pubmed/28860625
http://dx.doi.org/10.1038/s41598-017-10545-1