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AMPK β1 reduces tumor progression and improves survival in p53 null mice
The AMP‐activated protein kinase (AMPK) is a heterotrimeric protein complex that is an important sensor of cellular energy status. Reduced expression of the AMPK β1 isoform has been linked to reduced survival in different cancers, but whether this accelerates tumor progression and the potential mech...
Autores principales: | Houde, Vanessa P., Donzelli, Sara, Sacconi, Andrea, Galic, Sandra, Hammill, Joanne A., Bramson, Jonathan L., Foster, Robert A., Tsakiridis, Theodoros, Kemp, Bruce E., Grasso, Giuseppe, Blandino, Giovanni, Muti, Paola, Steinberg, Gregory R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579332/ https://www.ncbi.nlm.nih.gov/pubmed/28544264 http://dx.doi.org/10.1002/1878-0261.12079 |
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