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APP mouse models for Alzheimer's disease preclinical studies

Animal models of human diseases that accurately recapitulate clinical pathology are indispensable for understanding molecular mechanisms and advancing preclinical studies. The Alzheimer's disease (AD) research community has historically used first‐generation transgenic (Tg) mouse models that ov...

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Detalles Bibliográficos
Autores principales:	Sasaguri, Hiroki, Nilsson, Per, Hashimoto, Shoko, Nagata, Kenichi, Saito, Takashi, De Strooper, Bart, Hardy, John, Vassar, Robert, Winblad, Bengt, Saido, Takaomi C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579350/ https://www.ncbi.nlm.nih.gov/pubmed/28768718 http://dx.doi.org/10.15252/embj.201797397

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