Déficit congénital en facteur V: à propos d’un cas

Factor V congenital deficiency is a rare coagulation disorder initially described by Owren in 1947 and known as para hemophilia. It is transmitted through autosomal-recessive inheritance and homozygous cases are usually symptomatic. Factor V is an essential cofactor in the conversion of prothrombin...

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Autores principales: Boujrad, Saloua, El Hasbaoui, Brahim, Echahdi, Hanae, Malih, Mohamed, Agadr, Aomar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579429/
https://www.ncbi.nlm.nih.gov/pubmed/28904709
http://dx.doi.org/10.11604/pamj.2017.27.182.12285
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author Boujrad, Saloua
El Hasbaoui, Brahim
Echahdi, Hanae
Malih, Mohamed
Agadr, Aomar
author_facet Boujrad, Saloua
El Hasbaoui, Brahim
Echahdi, Hanae
Malih, Mohamed
Agadr, Aomar
author_sort Boujrad, Saloua
collection PubMed
description Factor V congenital deficiency is a rare coagulation disorder initially described by Owren in 1947 and known as para hemophilia. It is transmitted through autosomal-recessive inheritance and homozygous cases are usually symptomatic. Factor V is an essential cofactor in the conversion of prothrombin to thrombin by activated factor X. In the absence of factor V, thrombin generation is slowed down and fibrin formation is delayed. This results in a bleeding tendency. We report a case of factor V congenital deficiency in an infant with recurrent epistaxis.
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spelling pubmed-55794292017-09-13 Déficit congénital en facteur V: à propos d’un cas Boujrad, Saloua El Hasbaoui, Brahim Echahdi, Hanae Malih, Mohamed Agadr, Aomar Pan Afr Med J Case Report Factor V congenital deficiency is a rare coagulation disorder initially described by Owren in 1947 and known as para hemophilia. It is transmitted through autosomal-recessive inheritance and homozygous cases are usually symptomatic. Factor V is an essential cofactor in the conversion of prothrombin to thrombin by activated factor X. In the absence of factor V, thrombin generation is slowed down and fibrin formation is delayed. This results in a bleeding tendency. We report a case of factor V congenital deficiency in an infant with recurrent epistaxis. The African Field Epidemiology Network 2017-07-06 /pmc/articles/PMC5579429/ /pubmed/28904709 http://dx.doi.org/10.11604/pamj.2017.27.182.12285 Text en © Saloua Boujrad et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Boujrad, Saloua
El Hasbaoui, Brahim
Echahdi, Hanae
Malih, Mohamed
Agadr, Aomar
Déficit congénital en facteur V: à propos d’un cas
title Déficit congénital en facteur V: à propos d’un cas
title_full Déficit congénital en facteur V: à propos d’un cas
title_fullStr Déficit congénital en facteur V: à propos d’un cas
title_full_unstemmed Déficit congénital en facteur V: à propos d’un cas
title_short Déficit congénital en facteur V: à propos d’un cas
title_sort déficit congénital en facteur v: à propos d’un cas
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579429/
https://www.ncbi.nlm.nih.gov/pubmed/28904709
http://dx.doi.org/10.11604/pamj.2017.27.182.12285
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