Is Depression the Result of Immune System Abnormalities?

The etiology of Major Depressive Disorder (MDD) is still unclear. We reviewed the literature for the relationship between inflammatory signaling and cytokines in the pathogenesis of MDD. In addition, we provid evidence for adjunctive treatment using anti-inflammatory drugs to improve the therapeutic...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shanghai Municipal Bureau of Publishing 2017
Materias:
Forum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579461/
https://www.ncbi.nlm.nih.gov/pubmed/28904512
http://dx.doi.org/10.11919/j.issn.1002-0829.217015
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collection PubMed
description The etiology of Major Depressive Disorder (MDD) is still unclear. We reviewed the literature for the relationship between inflammatory signaling and cytokines in the pathogenesis of MDD. In addition, we provid evidence for adjunctive treatment using anti-inflammatory drugs to improve the therapeutic effect and prognosis. Finally, we explore the possible relationship between the pathogenesis of MDD and immune disturbances.
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spelling pubmed-55794612017-09-13 Is Depression the Result of Immune System Abnormalities? Shanghai Arch Psychiatry Forum The etiology of Major Depressive Disorder (MDD) is still unclear. We reviewed the literature for the relationship between inflammatory signaling and cytokines in the pathogenesis of MDD. In addition, we provid evidence for adjunctive treatment using anti-inflammatory drugs to improve the therapeutic effect and prognosis. Finally, we explore the possible relationship between the pathogenesis of MDD and immune disturbances. Shanghai Municipal Bureau of Publishing 2017-06-25 2017-06-25 /pmc/articles/PMC5579461/ /pubmed/28904512 http://dx.doi.org/10.11919/j.issn.1002-0829.217015 Text en © Shanghai Municipal Bureau of Publishing http://creativecommons.org/licenses/by-nc/4.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/
spellingShingle Forum
Is Depression the Result of Immune System Abnormalities?
title Is Depression the Result of Immune System Abnormalities?
title_full Is Depression the Result of Immune System Abnormalities?
title_fullStr Is Depression the Result of Immune System Abnormalities?
title_full_unstemmed Is Depression the Result of Immune System Abnormalities?
title_short Is Depression the Result of Immune System Abnormalities?
title_sort is depression the result of immune system abnormalities?
topic Forum
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579461/
https://www.ncbi.nlm.nih.gov/pubmed/28904512
http://dx.doi.org/10.11919/j.issn.1002-0829.217015
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