ecoAO: A Simple System for the Study of Human Aldehyde Oxidases Role in Drug Metabolism

[Image: see text] Although aldehyde oxidase (AO) is an important hepatic drug-metabolizing enzyme, it remains understudied and is consequently often overlooked in preclinical studies, an oversight that has resulted in the failure of multiple clinical trials. AO’s preclusion to investigation stems fr...

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Detalles Bibliográficos
Autores principales: Paragas, Erickson M., Humphreys, Sara C., Min, Joshua, Joswig-Jones, Carolyn A., Leimkühler, Silke, Jones, Jeffrey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579547/
https://www.ncbi.nlm.nih.gov/pubmed/28884164
http://dx.doi.org/10.1021/acsomega.7b01054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579547/
https://www.ncbi.nlm.nih.gov/pubmed/28884164
http://dx.doi.org/10.1021/acsomega.7b01054

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