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ecoAO: A Simple System for the Study of Human Aldehyde Oxidases Role in Drug Metabolism
[Image: see text] Although aldehyde oxidase (AO) is an important hepatic drug-metabolizing enzyme, it remains understudied and is consequently often overlooked in preclinical studies, an oversight that has resulted in the failure of multiple clinical trials. AO’s preclusion to investigation stems fr...
Autores principales: | Paragas, Erickson M., Humphreys, Sara C., Min, Joshua, Joswig-Jones, Carolyn A., Leimkühler, Silke, Jones, Jeffrey P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579547/ https://www.ncbi.nlm.nih.gov/pubmed/28884164 http://dx.doi.org/10.1021/acsomega.7b01054 |
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