Abrogation of Immunogenic Properties of Gliadin Peptides through Transamidation by Microbial Transglutaminase Is Acyl-Acceptor Dependent

[Image: see text] Wheat gluten confers superior baking quality to wheat based products but elicits a pro-inflammatory immune response in patients with celiac disease. Transamidation of gluten by microbial transglutaminase (mTG) and tissue transglutaminase (tTG) reduces the immunogenicity of gluten;...

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Autores principales: Zhou, Lin, Kooy-Winkelaar, Yvonne M. C., Cordfunke, Robert A., Dragan, Irina, Thompson, Allan, Drijfhout, Jan Wouter, van Veelen, Peter A., Chen, Hongbing, Koning, Frits
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579586/
https://www.ncbi.nlm.nih.gov/pubmed/28771001
http://dx.doi.org/10.1021/acs.jafc.7b02557

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