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Diet Quality throughout Early Life in Relation to Allergic Sensitization and Atopic Diseases in Childhood

Early-life nutrition is an important modifiable determinant in the development of a child’s immune system, and may thereby influence the risk of allergic sensitization and atopic diseases. However, associations between overall dietary patterns and atopic diseases in childhood remain unclear. We exam...

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Autores principales: Nguyen, Anh N., Elbert, Niels J., Pasmans, Suzanne G. M. A., Kiefte-de Jong, Jessica C., de Jong, Nicolette W., Moll, Henriëtte A., Jaddoe, Vincent W. V., de Jongste, Johan C., Franco, Oscar H., Duijts, Liesbeth, Voortman, Trudy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579634/
https://www.ncbi.nlm.nih.gov/pubmed/28783056
http://dx.doi.org/10.3390/nu9080841
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author Nguyen, Anh N.
Elbert, Niels J.
Pasmans, Suzanne G. M. A.
Kiefte-de Jong, Jessica C.
de Jong, Nicolette W.
Moll, Henriëtte A.
Jaddoe, Vincent W. V.
de Jongste, Johan C.
Franco, Oscar H.
Duijts, Liesbeth
Voortman, Trudy
author_facet Nguyen, Anh N.
Elbert, Niels J.
Pasmans, Suzanne G. M. A.
Kiefte-de Jong, Jessica C.
de Jong, Nicolette W.
Moll, Henriëtte A.
Jaddoe, Vincent W. V.
de Jongste, Johan C.
Franco, Oscar H.
Duijts, Liesbeth
Voortman, Trudy
author_sort Nguyen, Anh N.
collection PubMed
description Early-life nutrition is an important modifiable determinant in the development of a child’s immune system, and may thereby influence the risk of allergic sensitization and atopic diseases. However, associations between overall dietary patterns and atopic diseases in childhood remain unclear. We examined associations of diet quality in early life with allergic sensitization, self-reported physician-diagnosed inhalant and food allergies, eczema, and asthma among 5225 children participating in a population-based cohort in the Netherlands. Diet was assessed during pregnancy, infancy, and childhood using validated food-frequency questionnaires. We calculated food-based diet quality scores (0–10 or 0–15), reflecting adherence to dietary guidelines. At age 10 years, allergic sensitization was assessed with skin prick tests. Information on physician-diagnosed inhalant and food allergies, eczema, and asthma was obtained with questionnaires. We observed no associations between diet quality during pregnancy and allergic sensitization (odds ratio (OR) = 1.05 per point in the diet score, 95% confidence interval (CI): 0.99, 1.13), allergies (0.96, 95% CI: 0.88, 1.04), eczema (0.99, 95% CI: 0.93, 1.06), or asthma (0.93, 95% CI: 0.85, 1.03) in childhood. Also, diet quality in infancy or childhood were not associated with atopic outcomes in childhood. Our findings do not support our hypothesis that a healthy dietary pattern in early life is associated with a lower risk of allergic sensitization or atopic diseases in childhood.
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spelling pubmed-55796342017-09-06 Diet Quality throughout Early Life in Relation to Allergic Sensitization and Atopic Diseases in Childhood Nguyen, Anh N. Elbert, Niels J. Pasmans, Suzanne G. M. A. Kiefte-de Jong, Jessica C. de Jong, Nicolette W. Moll, Henriëtte A. Jaddoe, Vincent W. V. de Jongste, Johan C. Franco, Oscar H. Duijts, Liesbeth Voortman, Trudy Nutrients Article Early-life nutrition is an important modifiable determinant in the development of a child’s immune system, and may thereby influence the risk of allergic sensitization and atopic diseases. However, associations between overall dietary patterns and atopic diseases in childhood remain unclear. We examined associations of diet quality in early life with allergic sensitization, self-reported physician-diagnosed inhalant and food allergies, eczema, and asthma among 5225 children participating in a population-based cohort in the Netherlands. Diet was assessed during pregnancy, infancy, and childhood using validated food-frequency questionnaires. We calculated food-based diet quality scores (0–10 or 0–15), reflecting adherence to dietary guidelines. At age 10 years, allergic sensitization was assessed with skin prick tests. Information on physician-diagnosed inhalant and food allergies, eczema, and asthma was obtained with questionnaires. We observed no associations between diet quality during pregnancy and allergic sensitization (odds ratio (OR) = 1.05 per point in the diet score, 95% confidence interval (CI): 0.99, 1.13), allergies (0.96, 95% CI: 0.88, 1.04), eczema (0.99, 95% CI: 0.93, 1.06), or asthma (0.93, 95% CI: 0.85, 1.03) in childhood. Also, diet quality in infancy or childhood were not associated with atopic outcomes in childhood. Our findings do not support our hypothesis that a healthy dietary pattern in early life is associated with a lower risk of allergic sensitization or atopic diseases in childhood. MDPI 2017-08-05 /pmc/articles/PMC5579634/ /pubmed/28783056 http://dx.doi.org/10.3390/nu9080841 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nguyen, Anh N.
Elbert, Niels J.
Pasmans, Suzanne G. M. A.
Kiefte-de Jong, Jessica C.
de Jong, Nicolette W.
Moll, Henriëtte A.
Jaddoe, Vincent W. V.
de Jongste, Johan C.
Franco, Oscar H.
Duijts, Liesbeth
Voortman, Trudy
Diet Quality throughout Early Life in Relation to Allergic Sensitization and Atopic Diseases in Childhood
title Diet Quality throughout Early Life in Relation to Allergic Sensitization and Atopic Diseases in Childhood
title_full Diet Quality throughout Early Life in Relation to Allergic Sensitization and Atopic Diseases in Childhood
title_fullStr Diet Quality throughout Early Life in Relation to Allergic Sensitization and Atopic Diseases in Childhood
title_full_unstemmed Diet Quality throughout Early Life in Relation to Allergic Sensitization and Atopic Diseases in Childhood
title_short Diet Quality throughout Early Life in Relation to Allergic Sensitization and Atopic Diseases in Childhood
title_sort diet quality throughout early life in relation to allergic sensitization and atopic diseases in childhood
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579634/
https://www.ncbi.nlm.nih.gov/pubmed/28783056
http://dx.doi.org/10.3390/nu9080841
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