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Characteristics of Abdominal Aortic Aneurysm in Japanese Patients Aged 50 Years or Younger

Objective: We investigated the characteristics and surgical outcomes of abdominal aortic aneurysm (AAA), which typically occurs in elderly persons, in Japanese patients aged 50 years or younger. Materials and Methods: Clinical records of 999 patients who underwent open or endovascular repair for AAA...

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Autores principales: Nakano, Mitsunori, Kimura, Naoyuki, Matsumoto, Harunobu, Hirano, Tomoyasu, Adachi, Koichi, Yuri, Koichi, Yamaguchi, Atsushi, Adachi, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese College of Angiology / The Japanese Society for Vascular Surgery / Japanese Society of Phlebology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579777/
https://www.ncbi.nlm.nih.gov/pubmed/29034037
http://dx.doi.org/10.3400/avd.oa.16-00083
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author Nakano, Mitsunori
Kimura, Naoyuki
Matsumoto, Harunobu
Hirano, Tomoyasu
Adachi, Koichi
Yuri, Koichi
Yamaguchi, Atsushi
Adachi, Hideo
author_facet Nakano, Mitsunori
Kimura, Naoyuki
Matsumoto, Harunobu
Hirano, Tomoyasu
Adachi, Koichi
Yuri, Koichi
Yamaguchi, Atsushi
Adachi, Hideo
author_sort Nakano, Mitsunori
collection PubMed
description Objective: We investigated the characteristics and surgical outcomes of abdominal aortic aneurysm (AAA), which typically occurs in elderly persons, in Japanese patients aged 50 years or younger. Materials and Methods: Clinical records of 999 patients who underwent open or endovascular repair for AAA at our hospital between 2007 and 2015 were reviewed to identify the clinical characteristics and surgical outcomes of young patients with AAA. The cohort included 14 patients aged 50 years or younger (mean, 40.4 years; young group) and 985 patients aged older than 50 years (mean, 72.8 years; old group). Results: Marfan syndrome, prior aortic dissection, and a history of aortic surgery were more prevalent in the young group, and 50% of the patients in the young group had dissecting aneurysms. All patients in the young group underwent open repair. Overall in-hospital mortality rates were 7.1% (1/14) and 1.9% (19/985) in the young and old groups, respectively (P=0.67). Seven-year survival and aortic event-free survival rates in the young group were 82.5%±11.5%, and 71.2±14.5%, respectively. Conclusion: AAA in patients aged 50 years or younger tended to be associated with Marfan syndrome, a history of aortic surgery, and prior aortic dissection. Early outcomes of AAA among young patients are acceptable, but close postoperative monitoring is important.
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spelling pubmed-55797772017-10-13 Characteristics of Abdominal Aortic Aneurysm in Japanese Patients Aged 50 Years or Younger Nakano, Mitsunori Kimura, Naoyuki Matsumoto, Harunobu Hirano, Tomoyasu Adachi, Koichi Yuri, Koichi Yamaguchi, Atsushi Adachi, Hideo Ann Vasc Dis Original Article Objective: We investigated the characteristics and surgical outcomes of abdominal aortic aneurysm (AAA), which typically occurs in elderly persons, in Japanese patients aged 50 years or younger. Materials and Methods: Clinical records of 999 patients who underwent open or endovascular repair for AAA at our hospital between 2007 and 2015 were reviewed to identify the clinical characteristics and surgical outcomes of young patients with AAA. The cohort included 14 patients aged 50 years or younger (mean, 40.4 years; young group) and 985 patients aged older than 50 years (mean, 72.8 years; old group). Results: Marfan syndrome, prior aortic dissection, and a history of aortic surgery were more prevalent in the young group, and 50% of the patients in the young group had dissecting aneurysms. All patients in the young group underwent open repair. Overall in-hospital mortality rates were 7.1% (1/14) and 1.9% (19/985) in the young and old groups, respectively (P=0.67). Seven-year survival and aortic event-free survival rates in the young group were 82.5%±11.5%, and 71.2±14.5%, respectively. Conclusion: AAA in patients aged 50 years or younger tended to be associated with Marfan syndrome, a history of aortic surgery, and prior aortic dissection. Early outcomes of AAA among young patients are acceptable, but close postoperative monitoring is important. Japanese College of Angiology / The Japanese Society for Vascular Surgery / Japanese Society of Phlebology 2017-06-25 /pmc/articles/PMC5579777/ /pubmed/29034037 http://dx.doi.org/10.3400/avd.oa.16-00083 Text en Copyright © 2017 Annals of Vascular Diseases http://creativecommons.org/licenses/by-nc-sa/4.0/ This article is distributed under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided the credit of the original work, a link to the license, and indication of any change are properly given, and the original work is not used for commercial purposes. Remixed or transformed contributions must be distributed under the same license as the original.
spellingShingle Original Article
Nakano, Mitsunori
Kimura, Naoyuki
Matsumoto, Harunobu
Hirano, Tomoyasu
Adachi, Koichi
Yuri, Koichi
Yamaguchi, Atsushi
Adachi, Hideo
Characteristics of Abdominal Aortic Aneurysm in Japanese Patients Aged 50 Years or Younger
title Characteristics of Abdominal Aortic Aneurysm in Japanese Patients Aged 50 Years or Younger
title_full Characteristics of Abdominal Aortic Aneurysm in Japanese Patients Aged 50 Years or Younger
title_fullStr Characteristics of Abdominal Aortic Aneurysm in Japanese Patients Aged 50 Years or Younger
title_full_unstemmed Characteristics of Abdominal Aortic Aneurysm in Japanese Patients Aged 50 Years or Younger
title_short Characteristics of Abdominal Aortic Aneurysm in Japanese Patients Aged 50 Years or Younger
title_sort characteristics of abdominal aortic aneurysm in japanese patients aged 50 years or younger
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579777/
https://www.ncbi.nlm.nih.gov/pubmed/29034037
http://dx.doi.org/10.3400/avd.oa.16-00083
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