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Challenges of diagnosis and management of axial spondyloarthritis in North Africa and the Middle East: An expert consensus

Axial spondyloarthritis (SpA) is a spectrum of inflammatory disease with stages characterized by both nonradiographic and radiographic sacroiliitis. Nonradiographic axial SpA is associated with health-related quality-of-life impairment and may progress to ankylosing spondylitis. Axial SpA has a low...

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Autores principales: Hammoudeh, Mohammed, Abdulaziz, Sultana, Alosaimi, Hanan, Al-Rayes, Hanan, Aldeen Sarakbi, Hussam, Baamer, Matouqa, Baraliakos, Xenofon, Dahou Makhloufi, Chafia, Janoudi, Nahid, Shirazy, Khalid, Sieper, Joachim, Sukhbir, Uppal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580068/
https://www.ncbi.nlm.nih.gov/pubmed/26811411
http://dx.doi.org/10.1177/0300060515611536
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author Hammoudeh, Mohammed
Abdulaziz, Sultana
Alosaimi, Hanan
Al-Rayes, Hanan
Aldeen Sarakbi, Hussam
Baamer, Matouqa
Baraliakos, Xenofon
Dahou Makhloufi, Chafia
Janoudi, Nahid
Shirazy, Khalid
Sieper, Joachim
Sukhbir, Uppal
author_facet Hammoudeh, Mohammed
Abdulaziz, Sultana
Alosaimi, Hanan
Al-Rayes, Hanan
Aldeen Sarakbi, Hussam
Baamer, Matouqa
Baraliakos, Xenofon
Dahou Makhloufi, Chafia
Janoudi, Nahid
Shirazy, Khalid
Sieper, Joachim
Sukhbir, Uppal
author_sort Hammoudeh, Mohammed
collection PubMed
description Axial spondyloarthritis (SpA) is a spectrum of inflammatory disease with stages characterized by both nonradiographic and radiographic sacroiliitis. Nonradiographic axial SpA is associated with health-related quality-of-life impairment and may progress to ankylosing spondylitis. Axial SpA has a low prevalence in some countries in North Africa and the Middle East, and pooling of data and resources is needed to increase understanding of the regional picture. Early diagnosis and effective treatment are required to reduce disease burden and prevent progression. Anti-TNF therapy is recommended for patients with persistently high disease activity despite conventional treatment, and has been shown to be effective in patients without radiographic damage. Diagnostic delays can be an obstacle to early treatment and appropriate referral strategies are needed. In some countries, restricted access to magnetic resonance imaging and anti-TNF agents presents a challenge. In this article, a group of experts from North Africa and the Middle East evaluated the diagnosis and management of axial SpA with particular reference to this region.
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spelling pubmed-55800682017-10-03 Challenges of diagnosis and management of axial spondyloarthritis in North Africa and the Middle East: An expert consensus Hammoudeh, Mohammed Abdulaziz, Sultana Alosaimi, Hanan Al-Rayes, Hanan Aldeen Sarakbi, Hussam Baamer, Matouqa Baraliakos, Xenofon Dahou Makhloufi, Chafia Janoudi, Nahid Shirazy, Khalid Sieper, Joachim Sukhbir, Uppal J Int Med Res Review Axial spondyloarthritis (SpA) is a spectrum of inflammatory disease with stages characterized by both nonradiographic and radiographic sacroiliitis. Nonradiographic axial SpA is associated with health-related quality-of-life impairment and may progress to ankylosing spondylitis. Axial SpA has a low prevalence in some countries in North Africa and the Middle East, and pooling of data and resources is needed to increase understanding of the regional picture. Early diagnosis and effective treatment are required to reduce disease burden and prevent progression. Anti-TNF therapy is recommended for patients with persistently high disease activity despite conventional treatment, and has been shown to be effective in patients without radiographic damage. Diagnostic delays can be an obstacle to early treatment and appropriate referral strategies are needed. In some countries, restricted access to magnetic resonance imaging and anti-TNF agents presents a challenge. In this article, a group of experts from North Africa and the Middle East evaluated the diagnosis and management of axial SpA with particular reference to this region. SAGE Publications 2016-01-25 2016-04 /pmc/articles/PMC5580068/ /pubmed/26811411 http://dx.doi.org/10.1177/0300060515611536 Text en © The Author(s) 2016 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Hammoudeh, Mohammed
Abdulaziz, Sultana
Alosaimi, Hanan
Al-Rayes, Hanan
Aldeen Sarakbi, Hussam
Baamer, Matouqa
Baraliakos, Xenofon
Dahou Makhloufi, Chafia
Janoudi, Nahid
Shirazy, Khalid
Sieper, Joachim
Sukhbir, Uppal
Challenges of diagnosis and management of axial spondyloarthritis in North Africa and the Middle East: An expert consensus
title Challenges of diagnosis and management of axial spondyloarthritis in North Africa and the Middle East: An expert consensus
title_full Challenges of diagnosis and management of axial spondyloarthritis in North Africa and the Middle East: An expert consensus
title_fullStr Challenges of diagnosis and management of axial spondyloarthritis in North Africa and the Middle East: An expert consensus
title_full_unstemmed Challenges of diagnosis and management of axial spondyloarthritis in North Africa and the Middle East: An expert consensus
title_short Challenges of diagnosis and management of axial spondyloarthritis in North Africa and the Middle East: An expert consensus
title_sort challenges of diagnosis and management of axial spondyloarthritis in north africa and the middle east: an expert consensus
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580068/
https://www.ncbi.nlm.nih.gov/pubmed/26811411
http://dx.doi.org/10.1177/0300060515611536
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