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Next-generation disulfide stapling: reduction and functional re-bridging all in one

Herein we present a significant step towards next-generation disulfide stapling reagents. A novel class of reagent has been designed to effect both disulfide reduction and functional re-bridging. The strategy has been applied to great success across various peptides and proteins. Moreover, applicati...

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Detalles Bibliográficos
Autores principales:	Lee, Maximillian T. W., Maruani, Antoine, Baker, James R., Caddick, Stephen, Chudasama, Vijay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2016
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580075/ https://www.ncbi.nlm.nih.gov/pubmed/28966772 http://dx.doi.org/10.1039/c5sc02666k

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