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Sparse conserved under-methylated CpGs are associated with high-order chromatin structure

BACKGROUND: Whole-genome bisulfite sequencing (WGBS) is the gold standard for studying landscape DNA methylation. Current computational methods for WGBS are mainly designed for gene regulatory regions with multiple under-methylated CpGs (UMCs), such as promoters and enhancers. RESULTS: To reliably p...

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Detalles Bibliográficos
Autores principales:	Lin, Xueqiu, Su, Jianzhong, Chen, Kaifu, Rodriguez, Benjamin, Li, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580327/ https://www.ncbi.nlm.nih.gov/pubmed/28859663 http://dx.doi.org/10.1186/s13059-017-1296-x

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