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Modulation of electrostatic interactions to reveal a reaction network unifying the aggregation behaviour of the Aβ42 peptide and its variants

The aggregation of the amyloid β peptide (Aβ42), which is linked to Alzheimer's disease, can be altered significantly by modulations of the peptide's intermolecular electrostatic interactions. Variations in sequence and solution conditions have been found to lead to highly variable aggrega...

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Detalles Bibliográficos
Autores principales:	Meisl, Georg, Yang, Xiaoting, Dobson, Christopher M., Linse, Sara, Knowles, Tuomas P. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2017
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580342/ https://www.ncbi.nlm.nih.gov/pubmed/28979758 http://dx.doi.org/10.1039/c7sc00215g

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