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Pediatric liver failure: we came, we saw, but have we conquered?

Although there have been advances made in the diagnosis and management of pediatric acute liver failure, there is still no consensus regarding the definition or standardized evaluation, and an inability to predict outcomes, specifically irreversible brain injury, in many patients exists. Much of the...

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Detalles Bibliográficos
Autores principales: Smith, Sara Kathryn, Rosenthal, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580426/
https://www.ncbi.nlm.nih.gov/pubmed/28928955
http://dx.doi.org/10.12688/f1000research.9623.1
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author Smith, Sara Kathryn
Rosenthal, Philip
author_facet Smith, Sara Kathryn
Rosenthal, Philip
author_sort Smith, Sara Kathryn
collection PubMed
description Although there have been advances made in the diagnosis and management of pediatric acute liver failure, there is still no consensus regarding the definition or standardized evaluation, and an inability to predict outcomes, specifically irreversible brain injury, in many patients exists. Much of the research surrounding pediatric acute liver failure in the last several years has centered on the development of predictive scoring systems to enhance diagnosis and treatment decisions. In this article, we will discuss our current understanding of liver failure and updated management strategies in children with acute liver failure.
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spelling pubmed-55804262017-09-18 Pediatric liver failure: we came, we saw, but have we conquered? Smith, Sara Kathryn Rosenthal, Philip F1000Res Review Although there have been advances made in the diagnosis and management of pediatric acute liver failure, there is still no consensus regarding the definition or standardized evaluation, and an inability to predict outcomes, specifically irreversible brain injury, in many patients exists. Much of the research surrounding pediatric acute liver failure in the last several years has centered on the development of predictive scoring systems to enhance diagnosis and treatment decisions. In this article, we will discuss our current understanding of liver failure and updated management strategies in children with acute liver failure. F1000Research 2017-08-22 /pmc/articles/PMC5580426/ /pubmed/28928955 http://dx.doi.org/10.12688/f1000research.9623.1 Text en Copyright: © 2017 Smith SK and Rosenthal P http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Smith, Sara Kathryn
Rosenthal, Philip
Pediatric liver failure: we came, we saw, but have we conquered?
title Pediatric liver failure: we came, we saw, but have we conquered?
title_full Pediatric liver failure: we came, we saw, but have we conquered?
title_fullStr Pediatric liver failure: we came, we saw, but have we conquered?
title_full_unstemmed Pediatric liver failure: we came, we saw, but have we conquered?
title_short Pediatric liver failure: we came, we saw, but have we conquered?
title_sort pediatric liver failure: we came, we saw, but have we conquered?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580426/
https://www.ncbi.nlm.nih.gov/pubmed/28928955
http://dx.doi.org/10.12688/f1000research.9623.1
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