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HOXA1 and TALE proteins display cross-regulatory interactions and form a combinatorial binding code on HOXA1 targets

Hoxa1 has diverse functional roles in differentiation and development. We identify and characterize properties of regions bound by HOXA1 on a genome-wide basis in differentiating mouse ES cells. HOXA1-bound regions are enriched for clusters of consensus binding motifs for HOX, PBX, and MEIS, and man...

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Detalles Bibliográficos
Autores principales: De Kumar, Bony, Parker, Hugo J., Paulson, Ariel, Parrish, Mark E., Pushel, Irina, Singh, Narendra Pratap, Zhang, Ying, Slaughter, Brian D., Unruh, Jay R., Florens, Laurence, Zeitlinger, Julia, Krumlauf, Robb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580710/
https://www.ncbi.nlm.nih.gov/pubmed/28784834
http://dx.doi.org/10.1101/gr.219386.116