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HOXA1 and TALE proteins display cross-regulatory interactions and form a combinatorial binding code on HOXA1 targets
Hoxa1 has diverse functional roles in differentiation and development. We identify and characterize properties of regions bound by HOXA1 on a genome-wide basis in differentiating mouse ES cells. HOXA1-bound regions are enriched for clusters of consensus binding motifs for HOX, PBX, and MEIS, and man...
Autores principales: | De Kumar, Bony, Parker, Hugo J., Paulson, Ariel, Parrish, Mark E., Pushel, Irina, Singh, Narendra Pratap, Zhang, Ying, Slaughter, Brian D., Unruh, Jay R., Florens, Laurence, Zeitlinger, Julia, Krumlauf, Robb |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580710/ https://www.ncbi.nlm.nih.gov/pubmed/28784834 http://dx.doi.org/10.1101/gr.219386.116 |
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