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HIT'nDRIVE: patient-specific multidriver gene prioritization for precision oncology
Prioritizing molecular alterations that act as drivers of cancer remains a crucial bottleneck in therapeutic development. Here we introduce HIT'nDRIVE, a computational method that integrates genomic and transcriptomic data to identify a set of patient-specific, sequence-altered genes, with suff...
Autores principales: | Shrestha, Raunak, Hodzic, Ermin, Sauerwald, Thomas, Dao, Phuong, Wang, Kendric, Yeung, Jake, Anderson, Shawn, Vandin, Fabio, Haffari, Gholamreza, Collins, Colin C., Sahinalp, S. Cenk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580716/ https://www.ncbi.nlm.nih.gov/pubmed/28768687 http://dx.doi.org/10.1101/gr.221218.117 |
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