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E2/ER β inhibit ISO-induced cardiac cellular hypertrophy by suppressing Ca(2+)-calcineurin signaling
Cardiovascular incidences are markedly higher in men than in pre-menstrual women. However, this advantage in women declines with aging and therefore can be correlated with the sex hormone 17β-Estradiol (E2) which is reported to protect heart cells by acting though estrogen receptors (ERs). In this s...
Autores principales: | Tsai, Cheng-Yen, Kuo, Wei-Wen, Shibu, Marthandam Asokan, Lin, Yueh-Min, Liu, Chien-Nam, Chen, Yi-Hui, Day, Cecilia-Hsuan, Shen, Chia-Yao, Viswanadha, Vijaya Padma, Huang, Chih-Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580914/ https://www.ncbi.nlm.nih.gov/pubmed/28863192 http://dx.doi.org/10.1371/journal.pone.0184153 |
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