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Insertion of the voltage-sensitive domain into circularly permuted red fluorescent protein as a design for genetically encoded voltage sensor
Visualization of electrical activity in living cells represents an important challenge in context of basic neurophysiological studies. Here we report a new voltage sensitive fluorescent indicator which response could be detected by fluorescence monitoring in a single red channel. To the best of our...
Autores principales: | Kost, Liubov A., Nikitin, Evgeny S., Ivanova, Violetta O., Sung, Uhna, Putintseva, Ekaterina V., Chudakov, Dmitry M., Balaban, Pavel M., Lukyanov, Konstantin A., Bogdanov, Alexey M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580962/ https://www.ncbi.nlm.nih.gov/pubmed/28863184 http://dx.doi.org/10.1371/journal.pone.0184225 |
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