Association of high microvessel α(v)β(3) and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126

Neuroblastoma (NB) is the most common extracranial solid tumor in children. Our previous studies showed that the angiogenic integrin α(v)β(3) was increased in high-risk metastatic (stage 4) NB compared with localized neuroblastomas. Herein, we show that integrin α(v)β(3) was expressed on 68% of micr...

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Detalles Bibliográficos
Autores principales: Erdreich-Epstein, Anat, Singh, Alok R., Joshi, Shweta, Vega, Francisco M., Guo, Pinzheng, Xu, Jingying, Groshen, Susan, Ye, Wei, Millard, Melissa, Campan, Mihaela, Morales, Guillermo, Garlich, Joseph R., Laird, Peter W., Seeger, Robert C., Shimada, Hiroyuki, Durden, Donald L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581022/
https://www.ncbi.nlm.nih.gov/pubmed/28881723
http://dx.doi.org/10.18632/oncotarget.13386

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