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Whole tumor RNA-sequencing and deconvolution reveal a clinically-prognostic PTEN/PI3K-regulated glioma transcriptional signature
The concept that solid tumors are maintained by a productive interplay between neoplastic and non-neoplastic elements has gained traction with the demonstration that stromal fibroblasts and immune system cells dictate cancer development and progression. While less studied, brain tumor (glioma) biolo...
Autores principales: | Pan, Yuan, Bush, Erin C., Toonen, Joseph A., Ma, Yu, Solga, Anne C., Sims, Peter A., Gutmann, David H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581044/ https://www.ncbi.nlm.nih.gov/pubmed/28881745 http://dx.doi.org/10.18632/oncotarget.17193 |
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