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Selective Inhibitors of Nuclear Export (SINE) compounds block proliferation and migration of triple negative breast cancer cells by restoring expression of ARRDC3

Arrestin-related domain-containing protein-3 (ARRDC3) is one of 6 mammalian arrestins, which suppresses metastasis by inducing degradation of phosphorylated β2-adrenergic receptor (β2 AR) and integrin β4 (ITG β4). Our previous studies demonstrated that expression of ARRDC3 is epigentically silenced...

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Detalles Bibliográficos
Autores principales:	Soung, Young Hwa, Kashyap, Trinayan, Nguyen, Thalia, Yadav, Garima, Chang, Hua, Landesman, Yosef, Chung, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581083/ https://www.ncbi.nlm.nih.gov/pubmed/28881784 http://dx.doi.org/10.18632/oncotarget.17987

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