Cargando…

MiR-486-5p negatively regulates oncogenic NEK2 in hepatocellular carcinoma

NEK2 is a member of the NIMA-related family of serine/threonine centrosomal kinases. We analyzed the relationship between differential expression of NEK2 and hepatocellular carcinoma (HCC) patient outcomes after liver transplants. We also studied the microRNAs that affect NEK2 expression. Analysis o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fu, Shun-Jun, Chen, Jian, Ji, Fei, Ju, Wei-Qiang, Zhao, Qiang, Chen, Mao-Gen, Guo, Zhi-Yong, Wu, Lin-Wei, Ma, Yi, Wang, Dong-Ping, Zhu, Xiao-Feng, He, Xiao-Shun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581084/ https://www.ncbi.nlm.nih.gov/pubmed/28881785 http://dx.doi.org/10.18632/oncotarget.17635

Ejemplares similares

Exosome-Derived miR-486-5p Regulates Cell Cycle, Proliferation and Metastasis in Lung Adenocarcinoma via Targeting NEK2
por: Hu, Huihui, et al.
Publicado: (2020)

Retraction: Exosome-Derived miR-486-5p Regulates Cell Cycle, Proliferation and Metastasis in Lung Adenocarcinoma via Targeting NEK2
Publicado: (2021)

Direct repression of the oncogene CDK4 by the tumor suppressor miR-486-5p in non-small cell lung cancer
por: Shao, Yang, et al.
Publicado: (2016)

Elevated Preoperative Serum Gamma-glutamyltranspeptidase Predicts Poor Prognosis for Hepatocellular Carcinoma after Liver Transplantation
por: Fu, Shun-Jun, et al.
Publicado: (2016)

miR-486 as an unfavorable prognostic biomarker for patients with non-small cell lung cancer
por: Gao, Zhao-Jia, et al.
Publicado: (2020)

Prognostic value of combined preoperative fibrinogen and neutrophil–lymphocyte ratio in patients with hepatocellular carcinoma after liver transplantation
por: Fu, Shun-Jun, et al.
Publicado: (2016)

Expression and Prognostic Value of miR-486-5p in Patients with Gastric Adenocarcinoma
por: Chen, Hui, et al.
Publicado: (2015)

Downregulation of miR-486-5p in papillary thyroid carcinoma tissue: A study based on microarray and miRNA sequencing
por: Wen, Dong-Yue, et al.
Publicado: (2018)

miR-486 is modulated by stretch and increases ventricular growth
por: Lange, Stephan, et al.
Publicado: (2019)

The PAX3-FOXO1 oncogene alters exosome miRNA content and leads to paracrine effects mediated by exosomal miR-486
por: Ghamloush, Farah, et al.
Publicado: (2019)

miR-486 suppresses the development of osteosarcoma by regulating PKC-δ pathway
por: He, Ming, et al.
Publicado: (2017)

miR-486 suppresses the development of osteosarcoma by regulating PKC-δ pathway
por: He, Ming, et al.
Publicado: (2023)

Expression of circulating miR-486 and miR-150 in patients with acute myocardial infarction
por: Zhang, Rui, et al.
Publicado: (2015)

Decreased exosome-delivered miR-486-5p is responsible for the peritoneal metastasis of gastric cancer cells by promoting EMT progress
por: Lin, Xian-Ming, et al.
Publicado: (2021)

Down-regulation of miR-486-5p expression inhibits the proliferation and invasion of human extravillous trophoblasts, and decreased peripheral plasma miR-486-5p level is associated with human early pregnancy loss: Role of miR-486-5p in human early pregnancy loss
por: Gu, Yan, et al.
Publicado: (2023)

miR-486-3p mediates hepatocellular carcinoma sorafenib resistance by targeting FGFR4 and EGFR
por: Ji, Lin, et al.
Publicado: (2020)

MiR-486-5p Suppresses Proliferation and Migration of Hepatocellular Carcinoma Cells through Downregulation of the E3 Ubiquitin Ligase CBL
por: He, Jia, et al.
Publicado: (2019)

The Molecular Pathogenesis of Tumor-Suppressive miR-486-5p and miR-486-3p Target Genes: GINS4 Facilitates Aggressiveness in Lung Adenocarcinoma
por: Tomioka, Yuya, et al.
Publicado: (2023)

MiR-486 regulates cardiomyocyte apoptosis by p53-mediated BCL-2 associated mitochondrial apoptotic pathway
por: Sun, Yuhan, et al.
Publicado: (2017)

Silencing of miR-486 alleviates LPS-stimulated inflammatory response of macrophages through targeting SIRT1
por: Huang, Jie, et al.
Publicado: (2019)

miR-486-5p expression is regulated by DNA methylation in osteosarcoma
por: Namløs, Heidi M., et al.
Publicado: (2022)

miR-486 is essential for muscle function and suppresses a dystrophic transcriptome
por: Samani, Adrienne, et al.
Publicado: (2022)

Centrosomal kinase Nek2 cooperates with oncogenic pathways to promote metastasis
por: Das, T K, et al.
Publicado: (2013)

HDAC7 promotes the oncogenicity of nasopharyngeal carcinoma cells by miR-4465-EphA2 signaling axis
por: Li, Qi-Guang, et al.
Publicado: (2020)

Downregulation of KIAA1199 by miR‐486‐5p suppresses tumorigenesis in lung cancer
por: Wang, Anqi, et al.
Publicado: (2020)

miR-486-3p, miR-139-5p, and miR-21 as Biomarkers for the Detection of Oral Tongue Squamous Cell Carcinoma
por: Chen, Zujian, et al.
Publicado: (2017)

miR-486-3p, miR-139-5p, and miR-21 as Biomarkers for the Detection of Oral Tongue Squamous Cell Carcinoma
por: Chen, Zujian, et al.
Publicado: (2017)

miR-196b, miR-378a and miR-486 are predictive biomarkers for the efficacy of vaccine treatment in colorectal cancer
por: Shindo, Yoshitaro, et al.
Publicado: (2017)

NEK2 serves as a prognostic biomarker for hepatocellular carcinoma
por: Li, Gang, et al.
Publicado: (2017)

Downregulation of miR-486-5p Enhances the Anti-Tumor Effect of 5-Fluorouracil on Pancreatic Cancer Cells
por: Wang, Wei, et al.
Publicado: (2020)

MiR-486 Regulates Lactation and Targets the PTEN Gene in Cow Mammary Glands
por: Li, Dan, et al.
Publicado: (2015)

miR-486-5p: A Prognostic Biomarker for Chronic Myeloid Leukemia
por: Ninawe, Anupama, et al.
Publicado: (2021)

The miR-486-5p plays a causative role in prostate cancer through negative regulation of multiple tumor suppressor pathways
por: Yang, Yang, et al.
Publicado: (2017)

MicroRNA profiling reveals that miR-21, miR486 and miR-214 are upregulated and involved in cell survival in Sézary syndrome
por: Narducci, M G, et al.
Publicado: (2011)

NEK4 kinase regulates EMT to promote lung cancer metastasis
por: Ding, Nian‐Hua, et al.
Publicado: (2018)

Serum miR-486-5p as a diagnostic marker in cervical cancer: with investigation of potential mechanisms
por: Li, Chunmei, et al.
Publicado: (2018)

miR-486-5p and miR-22-3p Enable Megakaryocytic Differentiation of Hematopoietic Stem and Progenitor Cells without Thrombopoietin
por: Kao, Chen-Yuan, et al.
Publicado: (2022)

Elevated IgE promotes cardiac fibrosis by suppressing miR-486a-5p
por: Zhao, Hongmei, et al.
Publicado: (2021)

Circular RNA circHUWE1 Is Upregulated and Promotes Cell Proliferation, Migration and Invasion in Colorectal Cancer by Sponging miR-486
por: Chen, Hong-Yu, et al.
Publicado: (2020)

MIR22HG regulates miR-486/PTEN axis in bladder cancer to promote cell proliferation
por: Tang, Qisheng, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_fghj5g475vj0f6oul40oisudra