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miR-133b down-regulates ABCC1 and enhances the sensitivity of CRC to anti-tumor drugs

Multidrug resistance (MDR) is the main cause of failed chemotherapy treatments. Therefore, preventing MDR is pivotal in treating colorectal cancer (CRC). In a previous study miR-133b was shown to be a tumor suppressor. Additionally, in CRC cells transfected with miR-133b, ATP-binding cassette (ABC)...

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Detalles Bibliográficos
Autores principales: Chen, Miao, Li, Daojiang, Gong, Ni, Wu, Hao, Su, Chen, Xie, Canbin, Xiang, Hong, Lin, Changwei, Li, Xiaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581087/
https://www.ncbi.nlm.nih.gov/pubmed/28881788
http://dx.doi.org/10.18632/oncotarget.17677