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Down regulation of human positive coactivator 4 suppress tumorigenesis and lung metastasis of osteosarcoma
Osteosarcoma is a kind of primary malignant bone tumor with the highest incidence and an extraordinarily poor prognosis and early pulmonary metastasis formation as a frequent occurrence. Transcriptional positive coactivator 4 (PC4) has multiple functions in DNA replication, transcription, repair and...
Autores principales: | Hu, Xu, Zhang, Chao, Zhang, Ying, Hong, Christopher S., Chen, Wugui, Shen, Weiwei, Wang, Hongkai, He, Jianrong, Chen, Pei, Zhou, Yue, Shi, Chunmeng, Chu, Tongwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581104/ https://www.ncbi.nlm.nih.gov/pubmed/28881805 http://dx.doi.org/10.18632/oncotarget.18290 |
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