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Selective ATP hydrolysis inhibition in F1Fo ATP synthase enhances radiosensitivity in non-small-cell lung cancer cells (A549)

BACKGROUND: F1Fo-ATP synthase (F1Fo-ATPase) is a reversibly rotary molecular machine whose dual functions of synthesizing or hydrolyzing ATP switch upon the condition of cell physiology. The robust ATP-hydrolyzing activity occurs in ischemia for maintaining the transmembrane proton motive force of m...

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Detalles Bibliográficos
Autores principales: Wang, Yupei, Hou, Qinzheng, Xiao, Guoqing, Yang, Shifeng, Di, Cuixia, Si, Jing, Zhou, Rong, Ye, Yancheng, Zhang, Yanshan, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581133/
https://www.ncbi.nlm.nih.gov/pubmed/28881834
http://dx.doi.org/10.18632/oncotarget.18657

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