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A refined model of claudin-15 tight junction paracellular architecture by molecular dynamics simulations
Tight-junctions between epithelial cells of biological barriers are specialized molecular structures that regulate the flux of solutes across the barrier, parallel to cell walls. The tight-junction backbone is made of strands of transmembrane proteins from the claudin family, but the molecular mecha...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581167/ https://www.ncbi.nlm.nih.gov/pubmed/28863193 http://dx.doi.org/10.1371/journal.pone.0184190 |