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BRCA1 protein expression and subcellular localization in primary breast cancer: Automated digital microscopy analysis of tissue microarrays

PURPOSE: Mutations in BRCA1 are associated with familial as well as sporadic aggressive subtypes of breast cancer, but less is known about whether BRCA1 expression or subcellular localization contributes to progression in population-based settings. METHODS: We examined BRCA1 expression and subcellul...

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Detalles Bibliográficos
Autores principales: Mahmoud, Abeer M., Macias, Virgilia, Al-alem, Umaima, Deaton, Ryan J., Kadjaksy-Balla, Andre, Gann, Peter H., Rauscher, Garth H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581176/
https://www.ncbi.nlm.nih.gov/pubmed/28863181
http://dx.doi.org/10.1371/journal.pone.0184385