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Neutrophil Evolution and Their Diseases in Humans
Granulocytes have been preserved and have evolved across species, developing into cells that provide one of the first lines of host defense against pathogens. In humans, neutrophils are involved in early recognition and killing of infectious pathogens. Disruption in neutrophil production, emigration...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581313/ https://www.ncbi.nlm.nih.gov/pubmed/28894446 http://dx.doi.org/10.3389/fimmu.2017.01009 |
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author | Leiding, Jennifer W. |
author_facet | Leiding, Jennifer W. |
author_sort | Leiding, Jennifer W. |
collection | PubMed |
description | Granulocytes have been preserved and have evolved across species, developing into cells that provide one of the first lines of host defense against pathogens. In humans, neutrophils are involved in early recognition and killing of infectious pathogens. Disruption in neutrophil production, emigration, chemotaxis, and function cause a spectrum of primary immune defects characterized by host susceptibility to invasive infections. |
format | Online Article Text |
id | pubmed-5581313 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-55813132017-09-11 Neutrophil Evolution and Their Diseases in Humans Leiding, Jennifer W. Front Immunol Immunology Granulocytes have been preserved and have evolved across species, developing into cells that provide one of the first lines of host defense against pathogens. In humans, neutrophils are involved in early recognition and killing of infectious pathogens. Disruption in neutrophil production, emigration, chemotaxis, and function cause a spectrum of primary immune defects characterized by host susceptibility to invasive infections. Frontiers Media S.A. 2017-08-28 /pmc/articles/PMC5581313/ /pubmed/28894446 http://dx.doi.org/10.3389/fimmu.2017.01009 Text en Copyright © 2017 Leiding. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Immunology Leiding, Jennifer W. Neutrophil Evolution and Their Diseases in Humans |
title | Neutrophil Evolution and Their Diseases in Humans |
title_full | Neutrophil Evolution and Their Diseases in Humans |
title_fullStr | Neutrophil Evolution and Their Diseases in Humans |
title_full_unstemmed | Neutrophil Evolution and Their Diseases in Humans |
title_short | Neutrophil Evolution and Their Diseases in Humans |
title_sort | neutrophil evolution and their diseases in humans |
topic | Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581313/ https://www.ncbi.nlm.nih.gov/pubmed/28894446 http://dx.doi.org/10.3389/fimmu.2017.01009 |
work_keys_str_mv | AT leidingjenniferw neutrophilevolutionandtheirdiseasesinhumans |