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Hemodynamic Perturbations in Deep Brain Stimulation Surgery: First Detailed Description
Background: Hemodynamic perturbations can be anticipated in deep brain stimulation (DBS) surgery and may be attributed to multiple factors. Acute changes in hemodynamics may produce rare but severe complications such as intracranial bleeding, transient ischemic stroke and myocardium infarction. Ther...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581352/ https://www.ncbi.nlm.nih.gov/pubmed/28894414 http://dx.doi.org/10.3389/fnins.2017.00477 |
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author | Chowdhury, Tumul Wilkinson, Marshall Cappellani, Ronald B. |
author_facet | Chowdhury, Tumul Wilkinson, Marshall Cappellani, Ronald B. |
author_sort | Chowdhury, Tumul |
collection | PubMed |
description | Background: Hemodynamic perturbations can be anticipated in deep brain stimulation (DBS) surgery and may be attributed to multiple factors. Acute changes in hemodynamics may produce rare but severe complications such as intracranial bleeding, transient ischemic stroke and myocardium infarction. Therefore, this retrospective study attempts to determine the incidence of hemodynamic perturbances (rate) and related risk factors in patients undergoing DBS surgery. Materials and Methods: After institutional approval, all patients undergoing DBS surgery for the past 10 years were recruited for this study. Demographic characteristics, procedural characteristics and intraoperative hemodynamic changes were noted. Event rate was calculated and the effect of all the variables on hemodynamic perturbations was analyzed by regression model. Results: Total hemodynamic adverse events during DBS surgery was 10.8 (0–42) and treated in 57% of cases. Conclusion: Among all the perioperative variables, the baseline blood pressure including systolic, diastolic, and mean arterial pressure was found to have highly significant effect on these intraoperative hemodynamic perturbations. |
format | Online Article Text |
id | pubmed-5581352 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-55813522017-09-11 Hemodynamic Perturbations in Deep Brain Stimulation Surgery: First Detailed Description Chowdhury, Tumul Wilkinson, Marshall Cappellani, Ronald B. Front Neurosci Neuroscience Background: Hemodynamic perturbations can be anticipated in deep brain stimulation (DBS) surgery and may be attributed to multiple factors. Acute changes in hemodynamics may produce rare but severe complications such as intracranial bleeding, transient ischemic stroke and myocardium infarction. Therefore, this retrospective study attempts to determine the incidence of hemodynamic perturbances (rate) and related risk factors in patients undergoing DBS surgery. Materials and Methods: After institutional approval, all patients undergoing DBS surgery for the past 10 years were recruited for this study. Demographic characteristics, procedural characteristics and intraoperative hemodynamic changes were noted. Event rate was calculated and the effect of all the variables on hemodynamic perturbations was analyzed by regression model. Results: Total hemodynamic adverse events during DBS surgery was 10.8 (0–42) and treated in 57% of cases. Conclusion: Among all the perioperative variables, the baseline blood pressure including systolic, diastolic, and mean arterial pressure was found to have highly significant effect on these intraoperative hemodynamic perturbations. Frontiers Media S.A. 2017-08-28 /pmc/articles/PMC5581352/ /pubmed/28894414 http://dx.doi.org/10.3389/fnins.2017.00477 Text en Copyright © 2017 Chowdhury, Wilkinson and Cappellani. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Chowdhury, Tumul Wilkinson, Marshall Cappellani, Ronald B. Hemodynamic Perturbations in Deep Brain Stimulation Surgery: First Detailed Description |
title | Hemodynamic Perturbations in Deep Brain Stimulation Surgery: First Detailed Description |
title_full | Hemodynamic Perturbations in Deep Brain Stimulation Surgery: First Detailed Description |
title_fullStr | Hemodynamic Perturbations in Deep Brain Stimulation Surgery: First Detailed Description |
title_full_unstemmed | Hemodynamic Perturbations in Deep Brain Stimulation Surgery: First Detailed Description |
title_short | Hemodynamic Perturbations in Deep Brain Stimulation Surgery: First Detailed Description |
title_sort | hemodynamic perturbations in deep brain stimulation surgery: first detailed description |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581352/ https://www.ncbi.nlm.nih.gov/pubmed/28894414 http://dx.doi.org/10.3389/fnins.2017.00477 |
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