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Hemodynamic Perturbations in Deep Brain Stimulation Surgery: First Detailed Description

Background: Hemodynamic perturbations can be anticipated in deep brain stimulation (DBS) surgery and may be attributed to multiple factors. Acute changes in hemodynamics may produce rare but severe complications such as intracranial bleeding, transient ischemic stroke and myocardium infarction. Ther...

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Autores principales: Chowdhury, Tumul, Wilkinson, Marshall, Cappellani, Ronald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581352/
https://www.ncbi.nlm.nih.gov/pubmed/28894414
http://dx.doi.org/10.3389/fnins.2017.00477
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author Chowdhury, Tumul
Wilkinson, Marshall
Cappellani, Ronald B.
author_facet Chowdhury, Tumul
Wilkinson, Marshall
Cappellani, Ronald B.
author_sort Chowdhury, Tumul
collection PubMed
description Background: Hemodynamic perturbations can be anticipated in deep brain stimulation (DBS) surgery and may be attributed to multiple factors. Acute changes in hemodynamics may produce rare but severe complications such as intracranial bleeding, transient ischemic stroke and myocardium infarction. Therefore, this retrospective study attempts to determine the incidence of hemodynamic perturbances (rate) and related risk factors in patients undergoing DBS surgery. Materials and Methods: After institutional approval, all patients undergoing DBS surgery for the past 10 years were recruited for this study. Demographic characteristics, procedural characteristics and intraoperative hemodynamic changes were noted. Event rate was calculated and the effect of all the variables on hemodynamic perturbations was analyzed by regression model. Results: Total hemodynamic adverse events during DBS surgery was 10.8 (0–42) and treated in 57% of cases. Conclusion: Among all the perioperative variables, the baseline blood pressure including systolic, diastolic, and mean arterial pressure was found to have highly significant effect on these intraoperative hemodynamic perturbations.
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spelling pubmed-55813522017-09-11 Hemodynamic Perturbations in Deep Brain Stimulation Surgery: First Detailed Description Chowdhury, Tumul Wilkinson, Marshall Cappellani, Ronald B. Front Neurosci Neuroscience Background: Hemodynamic perturbations can be anticipated in deep brain stimulation (DBS) surgery and may be attributed to multiple factors. Acute changes in hemodynamics may produce rare but severe complications such as intracranial bleeding, transient ischemic stroke and myocardium infarction. Therefore, this retrospective study attempts to determine the incidence of hemodynamic perturbances (rate) and related risk factors in patients undergoing DBS surgery. Materials and Methods: After institutional approval, all patients undergoing DBS surgery for the past 10 years were recruited for this study. Demographic characteristics, procedural characteristics and intraoperative hemodynamic changes were noted. Event rate was calculated and the effect of all the variables on hemodynamic perturbations was analyzed by regression model. Results: Total hemodynamic adverse events during DBS surgery was 10.8 (0–42) and treated in 57% of cases. Conclusion: Among all the perioperative variables, the baseline blood pressure including systolic, diastolic, and mean arterial pressure was found to have highly significant effect on these intraoperative hemodynamic perturbations. Frontiers Media S.A. 2017-08-28 /pmc/articles/PMC5581352/ /pubmed/28894414 http://dx.doi.org/10.3389/fnins.2017.00477 Text en Copyright © 2017 Chowdhury, Wilkinson and Cappellani. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Chowdhury, Tumul
Wilkinson, Marshall
Cappellani, Ronald B.
Hemodynamic Perturbations in Deep Brain Stimulation Surgery: First Detailed Description
title Hemodynamic Perturbations in Deep Brain Stimulation Surgery: First Detailed Description
title_full Hemodynamic Perturbations in Deep Brain Stimulation Surgery: First Detailed Description
title_fullStr Hemodynamic Perturbations in Deep Brain Stimulation Surgery: First Detailed Description
title_full_unstemmed Hemodynamic Perturbations in Deep Brain Stimulation Surgery: First Detailed Description
title_short Hemodynamic Perturbations in Deep Brain Stimulation Surgery: First Detailed Description
title_sort hemodynamic perturbations in deep brain stimulation surgery: first detailed description
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581352/
https://www.ncbi.nlm.nih.gov/pubmed/28894414
http://dx.doi.org/10.3389/fnins.2017.00477
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