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Salutary effects of glibenclamide during the chronic phase of murine experimental autoimmune encephalomyelitis

BACKGROUND: In multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE), inflammation is perpetuated by both infiltrating leukocytes and astrocytes. Recent work implicated SUR1-TRPM4 channels, expressed mostly by astrocytes, in murine EAE. We tested the hypothesis that pharmacolog...

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Detalles Bibliográficos
Autores principales:	Gerzanich, Volodymyr, Makar, Tapas K., Guda, Poornachander Reddy, Kwon, Min Seong, Stokum, Jesse A., Woo, Seung Kyoon, Ivanova, Svetlana, Ivanov, Alexander, Mehta, Rupal I., Morris, Alexandra Brooke, Bryan, Joseph, Bever, Christopher T., Marc Simard, J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581426/ https://www.ncbi.nlm.nih.gov/pubmed/28865458 http://dx.doi.org/10.1186/s12974-017-0953-z

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