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Distinctive subgroups derived by cluster analysis based on pain and psychological symptoms in Swedish older adults with chronic pain – a population study (PainS65+)

BACKGROUND: Improved knowledge based on clinical features of chronic pain in older adults would be valuable in terms of patient-orientated approaches and would provide support for health care systems in optimizing health care resources. This study identifies subgroups based on pain and psychological...

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Autores principales: Larsson, Britt, Gerdle, Björn, Bernfort, Lars, Levin, Lars-Åke, Dragioti, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581449/
https://www.ncbi.nlm.nih.gov/pubmed/28865445
http://dx.doi.org/10.1186/s12877-017-0591-4
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author Larsson, Britt
Gerdle, Björn
Bernfort, Lars
Levin, Lars-Åke
Dragioti, Elena
author_facet Larsson, Britt
Gerdle, Björn
Bernfort, Lars
Levin, Lars-Åke
Dragioti, Elena
author_sort Larsson, Britt
collection PubMed
description BACKGROUND: Improved knowledge based on clinical features of chronic pain in older adults would be valuable in terms of patient-orientated approaches and would provide support for health care systems in optimizing health care resources. This study identifies subgroups based on pain and psychological symptoms among Swedish older adults in the general population and compares derived subgroups with respect to socio-demographics, health aspects, and health care costs. METHODS: This cross-sectional study uses data collected from four registers and one survey. The total sample comprised 2415 individuals ≥65 years old. A two-step cluster analysis was performed. Data on pain intensity, number of pain sites, anxiety, depression, and pain catastrophizing were used as classification variables. Differences in socio-demographics, quality of life, general health, insomnia, and health care costs among the clusters were investigated. Association of the clusters with the above parameters was further evaluated using multinomial logistic regression. RESULTS: Four major clusters were identified: Subgroup 1 (n = 325; 15%) – moderate pain and high psychological symptoms; Subgroup 2 (n = 516; 22%) – high pain and moderate psychological symptoms; Subgroup 3 (n = 686; 30%) – low pain and moderate psychological symptoms; and Subgroup 4 (n = 767; 33%) – low pain and low psychological symptoms. Significant differences were found between the four clusters with regard to age, sex, educational level, family status, quality of life, general health, insomnia, and health care costs. The multinomial logistic regression analysis revealed that Subgroups 1 and 2, compared to Subgroup 4, were significantly associated with decreased quality of life, decreased general health, and increased insomnia. Subgroup 3, compared to Subgroup 4, was associated with decreased general health and increased insomnia. In addition, compared to Subgroup 4, Subgroups 1 and 2 were significantly associated with higher health care costs. CONCLUSIONS: Two high risk clusters of older adults suffering from chronic pain; one mainly based on psychological symptoms and one mainly on pain intensity and pain spread, associated with decreased quality of life and health and increased health care costs were identified. Our findings indicate that subgroup-specific treatment will improve pain management and reduce health care costs. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12877-017-0591-4) contains supplementary material, which is available to authorized users.
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spelling pubmed-55814492017-09-06 Distinctive subgroups derived by cluster analysis based on pain and psychological symptoms in Swedish older adults with chronic pain – a population study (PainS65+) Larsson, Britt Gerdle, Björn Bernfort, Lars Levin, Lars-Åke Dragioti, Elena BMC Geriatr Research Article BACKGROUND: Improved knowledge based on clinical features of chronic pain in older adults would be valuable in terms of patient-orientated approaches and would provide support for health care systems in optimizing health care resources. This study identifies subgroups based on pain and psychological symptoms among Swedish older adults in the general population and compares derived subgroups with respect to socio-demographics, health aspects, and health care costs. METHODS: This cross-sectional study uses data collected from four registers and one survey. The total sample comprised 2415 individuals ≥65 years old. A two-step cluster analysis was performed. Data on pain intensity, number of pain sites, anxiety, depression, and pain catastrophizing were used as classification variables. Differences in socio-demographics, quality of life, general health, insomnia, and health care costs among the clusters were investigated. Association of the clusters with the above parameters was further evaluated using multinomial logistic regression. RESULTS: Four major clusters were identified: Subgroup 1 (n = 325; 15%) – moderate pain and high psychological symptoms; Subgroup 2 (n = 516; 22%) – high pain and moderate psychological symptoms; Subgroup 3 (n = 686; 30%) – low pain and moderate psychological symptoms; and Subgroup 4 (n = 767; 33%) – low pain and low psychological symptoms. Significant differences were found between the four clusters with regard to age, sex, educational level, family status, quality of life, general health, insomnia, and health care costs. The multinomial logistic regression analysis revealed that Subgroups 1 and 2, compared to Subgroup 4, were significantly associated with decreased quality of life, decreased general health, and increased insomnia. Subgroup 3, compared to Subgroup 4, was associated with decreased general health and increased insomnia. In addition, compared to Subgroup 4, Subgroups 1 and 2 were significantly associated with higher health care costs. CONCLUSIONS: Two high risk clusters of older adults suffering from chronic pain; one mainly based on psychological symptoms and one mainly on pain intensity and pain spread, associated with decreased quality of life and health and increased health care costs were identified. Our findings indicate that subgroup-specific treatment will improve pain management and reduce health care costs. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12877-017-0591-4) contains supplementary material, which is available to authorized users. BioMed Central 2017-09-02 /pmc/articles/PMC5581449/ /pubmed/28865445 http://dx.doi.org/10.1186/s12877-017-0591-4 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Larsson, Britt
Gerdle, Björn
Bernfort, Lars
Levin, Lars-Åke
Dragioti, Elena
Distinctive subgroups derived by cluster analysis based on pain and psychological symptoms in Swedish older adults with chronic pain – a population study (PainS65+)
title Distinctive subgroups derived by cluster analysis based on pain and psychological symptoms in Swedish older adults with chronic pain – a population study (PainS65+)
title_full Distinctive subgroups derived by cluster analysis based on pain and psychological symptoms in Swedish older adults with chronic pain – a population study (PainS65+)
title_fullStr Distinctive subgroups derived by cluster analysis based on pain and psychological symptoms in Swedish older adults with chronic pain – a population study (PainS65+)
title_full_unstemmed Distinctive subgroups derived by cluster analysis based on pain and psychological symptoms in Swedish older adults with chronic pain – a population study (PainS65+)
title_short Distinctive subgroups derived by cluster analysis based on pain and psychological symptoms in Swedish older adults with chronic pain – a population study (PainS65+)
title_sort distinctive subgroups derived by cluster analysis based on pain and psychological symptoms in swedish older adults with chronic pain – a population study (pains65+)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581449/
https://www.ncbi.nlm.nih.gov/pubmed/28865445
http://dx.doi.org/10.1186/s12877-017-0591-4
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