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Combination therapy of PKCζ and COX-2 inhibitors synergistically suppress melanoma metastasis

BACKGROUND: Metastatic malignant melanoma is one of the most aggressive malignancies and its treatment remains challenging. Recent studies demonstrate that the melanoma metastasis has correlations with the heightened activations of protein kinase C ζ (PKCζ) and cyclooxygenase-2 (COX-2) signaling pat...

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Detalles Bibliográficos
Autores principales:	Zhou, Ping, Qin, Jiaqi, Li, Yuan, Li, Guoxia, Wang, Yinsong, Zhang, Ning, Chen, Peng, Li, Chunyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581453/ https://www.ncbi.nlm.nih.gov/pubmed/28865485 http://dx.doi.org/10.1186/s13046-017-0585-2

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